San Francisco 49ers running back Isaac Guerendo was carted off the field in the first quarter against the Arizona Cardinals. The team announced that

The San Francisco 49ers will finish out their 2024 season with tight end George Kittle in the mix. Kittle was listed as ‘questionable’ on the Week 18 injury report because of ankle and hamstring issues. He was a non-participant in Wednesday’s practice, but returned on a limited basis for Thursday and Friday.

The Arizona Cardinals face the San Francisco 49ers in Week 18 at State Farm Stadium to close out the season. They want to finish with a win. They are down to backup and fourth-string tackles, and Michael Carter will start at running back. But the 49ers will have Josh Dobbs at quarterback, a rookie at running back and a depleted offensive line.