A deadly tornado outbreak ripped through Missouri, Illinois, Arkansas and Mississippi overnight Friday, leaving destruction, power outages and tragic loss in its wake.

"Get to the sturdiest structure you have access to and remain in place until the storms pass," the NWS told residents in Alabama on Saturday night, when multiple tornado warnings were issued. At least 250,

The most fatalities were in Missouri. Forecasters warned that tornadoes, hail and violent winds continue to threaten states in the Deep South, from Louisiana to Georgia.

Thousands of power outages were reported Saturday as a deadly severe weather outbreak moved across the Midwest and South.